Internet, Networking, & Security Antivirus How to Remove a Virus When Your Computer Won't Work Help! I can't access my system! by Mary Landesman Writer Mary Landesman is a former freelance contributor to Lifewire and a security expert. She was named as one of the women to watch in IT security. our editorial process LinkedIn Mary Landesman Updated on June 06, 2019 David Gould/Getty Images Antivirus Browsers Cloud Services Error Messages Family Tech Home Networking 5G Antivirus VPN Web Development Around the Web View More Tweet Share Email Trying to remove a computer virus or other malware infection can become a battle of wills between you and the attacker. Antivirus software can be a powerful ally, removing most of today's malware with ease. Occasionally, a really stubborn infector may put you at the forefront of the battle. Here's how to help you win. Get Safe Access to the Drive The best time to remove malware is when it's in a dormant state. Booting into Safe Mode can work but isn't always the best option. Some malware hooks into something called "winlogon," which means that if you can access Windows, the malware is already loaded. Other malware will register as the file handler for a particular file type, so any time that file type is loaded, the malware is launched first. Your best bet for thwarting these type of infectors is to create a Recovery CD and use it to access the infected system. If you plan to run antivirus or other utilities from a USB drive, you'll need to have that drive plugged in before you boot to the Recovery CD. You will first want to disable autorun in case the USB drive is infected with an autorun worm. Then shut down the computer, insert the USB drive, and boot the computer to the Recovery CD. The Recovery CD will not recognize the USB drive if it wasn't plugged in when the computer was booted up. Determine the Malware Load Points Malware, like any other active program, needs to load in order to do damage. Once you have safe access to the infected drive, begin by checking the common startup points for signs of the infection. A list of common startup points can be found in the AutoStart Entry Points guide and the list of ShellOpen command keys. This task is best performed by experienced users. Back up the registry before beginning in case you inadvertently delete or change a legitimate setting. Retake Your Controls Much of today's malware typically block access to the Task Manager or the Folder Options menu in Windows, or it makes other system changes that hamper discovery and removal efforts. After removing the malware (either manually or through the use of antivirus software), you'll need to reset these settings to regain normal access. Regain Access to the RegistryRe-Enable Task ManagerView Folder Options MenuOther How-To Guides Prevent Reinfection The best defense is a good offense. Secure your browser, patch your system, and follow these computer safety tips to avoid future infections.