The 9 Best Ergonomic Mice of 2021

Stop straining your wrists and while using the computer

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The Rundown
"The MX Master 3 is the latest and greatest wireless ergonomic mouse from Logitech."
"Perfect if you have no use for fancy features and just want a simple yet functional ergonomic mouse that won't break the bank."
"The Scroll Endurance is ideal for users who have to work on computers for long hours with a design that alleviates hand fatigue."
Best Compact:
Swiftpoint GT at Amazon
"With a weight of just .84 ounces, the Swiftpoint GT is light as a feather but packs in an expansive feature set that belies its diminutive size."
Best Wireless:
Anker AK-UBA at Amazon
"The Anker AK-UBA is the ideal wireless ergonomic mouse, with a thoughtful design that encourages healthy wrist and arm positions."
"The MX ERGO features an industry-leading trackball to create an ergonomic experience that marries extreme precision with personal comfort."
"The ProPoint can work on just about any surface with its 1,800 DPI sensor and it supports Bluetooth 4.0 and newer firmware than the GT."
Runner-Up, Best Design:
Logitech MX Vertical at Amazon
Runner-Up, Best with Trackball:
Kensington Pro Fit Ergo at Amazon

We tend to spend long hours at our computers, but the repetitive motions of typing and clicking can be tough on our wrists and fingers. If you’ve experienced hand cramps, soreness, or RSI, it might be time to upgrade to a computer mouse that’s more ergonomically friendly. An ergonomic mouse is designed to work via more natural hand and wrist movements, reducing pain and discomfort. As a result, they are shaped differently and usually require less grip strength than a normal mouse. 

There are plenty on the market, so which ergonomic mouse is the best? We’ve researched and ranked mice from a number of top brands, including Microsoft, Logitech, Razer, and Anker. When shopping for an ergonomic mouse, you’ll want to consider price, comfort, wireless capabilities, size, and battery usage. Here are some of the best ergonomic mice for every preference. 

If your needs are more specific you should also look at our list of best wireless mice and best mice for gaming.

Best Overall: Logitech MX Master 3

Logitech MX Master 3
What We Like
  • Useful scroll wheel

  • Comfortable and intuitive design

  • USB-C fast charging and long-lasting battery

  • Plenty of customization options

What We Don't Like
  • Expensive

  • Software can take some time to figure out

One of our top overall recommendations is the Logitech MX Master 3. It’s a reinvention of the traditional mouse, and it’s a real winner. The wireless MX Master 3 is an update on the previous model, with improved contouring for your palm and an improved scroll wheel, allowing you to quickly and accurately scroll through websites and text at a rate of up to 1,000 lines per second. The sensor itself is also improved, with a 4,000 DPI resolution for improved precision.

With eight buttons in total, the MX Master 3 has plenty of options for customization, controlled via the Logitech Options software. Users can increase productivity by creating shortcuts to apps like Adobe, Final Cut Pro, and the Microsoft Office suite. You can even copy and paste text, images, and files between them without needing to use an additional file transfer service. The mouse itself will work on any surface, even glass, and it supports USB-C fast charging, lasting up to 70 days on a full charge. It fits comfortably and smoothly in your palm, giving you easy access to every button and control. If your budget allows, we don’t think you’ll be disappointed with the MX Master 3.

“I like all the programmable shortcuts on the Logitech MX Master 3, which will save plenty of time when editing and working online.”Katie Dundas, Freelance Tech Writer

Best Budget: Anker Ergonomic Optical USB Wired Vertical Mouse

What We Like
  • Simple and functional

  • Vertical design protects your wrist

  • Premium product for a great price

What We Don't Like
  • Not wireless

  • Can be a bit slippery

The stylish and functional Ergonomic Optical USB Wired Vertical Mouse, from Anker, is a fantastic choice for anyone on a budget. You’ve got fewer fancy features, but you do get a high-quality vertical mouse for a fraction of the price of the other mice reviewed here. The stylish, angular mouse sits at a vertical angle, which helps to reduce discomfort on your hand and wrist. The vertical design is found in other, more expensive mice, making this product fantastic value. It’s not a wireless mouse, but it does offer precision and speed, plus optical tracking technology which lets the mouse operate smoothly on a wide variety of surfaces. 

Anker’s vertical mouse includes five buttons, making it easy to drag and drop or move large amounts of data. You’ve also got use of a scroll wheel to quickly move vertically up and down a page. The mouse has a 1.5m (4.9-foot) long cable and uses the standard USB Type-A for connecting with PCs. The Anker Ergonomic Wired Mouse is backed by an 18-month warranty, as well as a lifetime technical support guarantee.

Best Wired: J-Tech Digital Scroll Digital Wired Ergonomic Mouse

What We Like
  • Fast

  • Vertical design to alleviate hand fatigue

  • Detachable palm rest and tactile buttons

What We Don't Like
  • Heavy

If you’re looking for a mouse that will remain on one computer, you probably don’t need to bother with a wireless device. There are plenty of amazing wired mice, with the J-Tech Digital being a standout. This affordable mouse impresses with its unique take on the vertical design and we like the inclusion of the removable palm rest for extra comfort. It’s ideal for those who work long hours online, as the vertical design reduces tension and fatigue in your wrist and arm. The top DPI button lets you adjust the mouse's sensitivity on the fly, and there are multiple sensitivity modes (600/1000/1600 DPI) that you can choose from.

Users also have a scroll wheel for added control, along with buttons for front/back and left/right navigation. While the J-Tech Digital is designed to have a premium look and feel, which it does, one knock-on effect is that the mouse is heavier and bulkier than some of its competitors. Weighing around 4.16 ounces and compatible with both USB 2.0 and USB 3.0 ports, the J-Tech Digital Scroll Endurance is backed by a one-year free replacement warranty.

Best Compact: Swiftpoint GT

What We Like
  • Compact size and light weight

  • Supports wireless USB and Bluetooth

  • Integrated iOS and Windows apps/programs

What We Don't Like
  • Expensive

The tiny size of the Swiftpoint GT may surprise you, but it’s proof that an ergonomic mouse doesn’t need to be bulky. For such a small product, the GT packs in plenty of features. With a weight of just .84 ounces, Swiftpoint GT is light as a feather and it fits in the palm of your hand, making it ideal for travel, with a travel case included. At this stage, the GT is only configured for right-hand users, but hopefully, a left-hand model is coming soon. Its small size allows your hand to rest naturally around it, making it more comfortable than larger products. 

Users have the benefit of both USB and Bluetooth connectivity and the built-in battery can last two to four weeks on a full charge, depending upon usage. With the unique touch gesture technology, you can scroll and zoom on touchscreen devices effortlessly. With two buttons and a gesture stylus, it has a sensor resolution of 1250 DPI. However, some users report that the position of the scroll wheel isn’t intuitive. You’ve also got integration with key iOS and Windows apps, such as TeamViewer and Amazon Workspaces. While the price may seem large for such a tiny product, the GT is worth it, since no other companies are offering anything similar.

“Hard to believe how effective such as a small mouse can be when it comes to reducing wrist pain, plus it’s great for travel.”Katie Dundas, Freelance Tech Writer

Best Wireless: Anker AK-UBA

What We Like
  • Vertical shape for smoother movement and comfort

  • Button to toggle DPI resolutions

  • Great value

What We Don't Like
  • Requires AAA batteries

  • Some buttons aren’t positioned well for smaller hands

Having a thoughtful design and easy-to-use features, the Anker AK-UBA is the ideal wireless ergonomic mouse for all your computing needs.

Anker AK-UBA mouse has a vertical shape that encourages healthy wrist and arm positions, resulting in smoother movement and lesser overall muscle strain. It comes with 800/1200/1600 DPI resolutions, and a button lets you easily toggle between these. The standard left and right buttons are vertically mounted, and a scroll wheel sits between them. Two additional buttons — Previous and Next — allow you to browse the Web faster and better, and the whole package is backed by an 18-month warranty. The mouse is compatible with Windows, Linux, and macOS.

The AK-UBA wireless mouse from Anker is powered by two AAA batteries. When not in use, the 2.4G USB wireless receiver can be easily stashed away in a slot on the bottom of the mouse.

Best With Trackball: Logitech MX ERGO Trackball Mouse

Logitech MX ERGO Trackball Mouse
What We Like
  • Built-in trackball gives you accurate control

  • Adjustable hinge lets you control how your angle of use

  • Rechargeable battery

What We Don't Like
  • Fairly pricey

  • Tilt option only goes up to 20 degrees

Trackballs are extremely precise since their effective travel range in all directions is virtually limitless. The fact that they don't have to be constantly re-positioned also makes them convenient to use. Many ergonomic mice come with built-in trackballs, and Logitech's MX ERGO is the best among them.

The mouse comes with a unique adjustable hinge that allows you to adjust its angle for personalized comfort, resulting in up to 20 percent lesser muscular strain. The MX ERGO also lets you control two PCs (even those having different operating systems) and switch between them seamlessly, speeding up your workflow.

Its multi-device trackball can be used to share files between two computers using basic Copy and Paste commands. Using the companion Logitech Options software, you can easily configure flow and assign custom functions/tasks to mouse buttons. Speaking of, a dedicated button can be used to change the speed and accuracy of the cursor on the fly, while the precision scroll wheel comes with horizontal scrolling and middle-click functionalities. The MX ERGO has a sculpted shape and rubber-top grip, which ensures full palm and finger support for more comfortable control. Fast and accurate, the mouse's island-style keys are claimed to be able to stand up to 10 million clicks.

Logitech MX ERGO has a built-in rechargeable battery that can go up to four months on a full charge. Also, just one minute of charging can provide up to a full day of use.

Best Travel: Swiftpoint ProPoint Wireless Bluetooth Mouse

ProPoint Wireless Bluetooth Mouse
What We Like
  • Compact ergonomic pen grip

  • Small and lightweight

  • Built-in laser pointer is fantastic for presentations

What We Don't Like
  • High price point

  • User report it can occasionally freeze up

If you’re frequently traveling or presenting in varied locations, you need a compact, wireless mouse that you can take with you. Enter the Swiftpoint ProPoint Wireless Bluetooth Mouse. The snazzy, lightweight little mouse works via an ergonomic pen grip, using your thumb and index fingers, taking the pressure off your wrist. It’s also packed with features that will be useful for presenting, including a battery charge lasting up to four weeks (or a rapid 30-second charge for an hour of use), a built-in laser pointer, when used with PowerPoint. It’s also iPad compatible. You’ve also got access to three programmable buttons and six different button actions with tilt gestures, giving you all the features and functionality of a wireless mouse in a much smaller package.

All of these perks do come at a higher price, but it’s the ideal mouse for anyone needing a travel companion. It’s sure to appeal to the professional crowd who will appreciate all it can offer. Plus, with a 1,800 DPI sensor, you’ve got the accuracy and speed to work from anywhere.

Runner-Up, Best Design: Logitech MX Vertical

What We Like
  • Innovative vertical design

  • Impressive battery life

  • Syncs with up to three devices

What We Don't Like
  • Bulky shape takes some getting used to

  • No hyper-scrolling feature

It may look like a sculpture, but the Logitech’s MX Vertical is more than just a stylish accessory—it’s an effective, ergonomic mouse that may change the way you work online. We love the striking vertical design–almost like someone took a regular mouse and flipped it on its side. Your hand sits in a handshake position, and the design minimizes strain and twisting, which should reduce wrist pain. With a soft textured surface, you’ve got a natural grip and your hand won’t slide around.

The MX Vertical can connect to up to three devices, streamlining productivity. The 4000 DPI high-precision sensor means you can navigate your computer with precision—although there’s no hyper-scrolling for long documents. Both Bluetooth and USB are supported. The battery life is also impressive, giving you up to four months of use on a full charge, or three hours from a fast one-minute charge. Once you get used to using its unique design, this one may become a fast favorite.

Runner-Up, Best with Trackball: Kensington Pro Fit Ergo

What We Like
  • Ergonomically-friendly vertical design

  • Lots of buttons that can be customized

  • Easy to use software

What We Don't Like
  • Battery operated

  • Best suited for smaller hands

If you’re after a vertical ergonomic mouse with a trackball, consider the Pro Fit Ergo Vertical. It features a comfortable ergonomic design, at a 60° tilt, that will support your hand and wrist, along with a standout red trackball, designed for thumb-use with the right hand. It also features nine customizable buttons, giving you plenty of programming options that can be set up using Ergo’s KensingtonWorks software. The Pro Fit is both Bluetooth and wireless-enabled, with connectivity to up to three different devices. However, when it comes to connecting itself to a power source, it’s dependent on AA batteries—advertised with up to 18 months of battery life. 

The Pro Fit offers both speed and accuracy, giving you smooth control all over your computer screen. It’s easy to clean as well—one concern about trackballs is that they can become dusty and dirty, but the Pro Fit solves this by letting users easily remove the trackball for cleaning. Some reviewers report it’s awkward for larger hands, but it’s otherwise a top choice for anyone looking for trackball and lots of options to personalize.

Final Verdict

If you're feeling arm and wrist strain, an ergonomic mouse like the Logitech MX Master 3 may be what you need. The mouse is wireless, has a comfortable design that reduces strain without leasing precision on clicks. There's also some special features like speed-adaptive scroll to shift scrolling modes, and a unifying receiver and Bluetooth to connect to three devices at the same time and work between them. For a more affordable option, we like the Anker Ergonomic Wired Mouse. It's not wireless, but it's a vertical mouse which encourages a healthy grip position, and it has solid tracking and functionality.

About Our Trusted Experts

Katie Dundas is a freelance journalist and tech writer who frequently covers computer accessories, and she’s worked with a wide range of wireless mice.

Gannon Brugett has more than a decade of experience as a tech and photojournalist and photographer. He's familiar with computer equipment and peripherals, particularly when it comes to video and photo editing. He enjoyed the MX Master 2S for its high-quality build and comfort for long hours of work, not to mention its useful functionality.

Alice Newcome-Beill is Associate Commerce Editor at Lifewire. She's previously been published on PCMag, PC Gamer, and GamesRadar. She even built her own gaming rig, so there are few people who know computer peripherals better than her. Alice likes the Razer DeathAdder Elite for its precision, especially when it comes to MOBAs and fast-paced shooters.

David Dean has worked in IT for 15 years in a variety of roles. He's also the founder of his own travel technology website and travel blog making him very familiar with wireless mice, vertical mice, and just about any variation of computer mice.

What to Look for When Buying Ergonomic Mice

Comfort/Design - The obvious feature of an ergonomic mouse is comfort. One common type of design you'll see is vertical mice, where a mouse is shaped in a way so you grip it in a "handshake" position. This puts less strain on your arms and wrist, though there is a learning curve to get used to the new button layouts and movements. Another design you might encounter is one often used by Logitech, with a wider mouse with a larger thumb grip to rest your hand comfortably. It might come with additional buttons like a scroll wheel or trackball to make navigation easier.

Wired/Wireless - A wired ergonomic mouse has the advantage of not needing to be recharged. It can also work out of the box with less setup. However, the inclusion of a cable is annoying to some and clutters desks. If you like to a clean workspace or are often working across multiple devices, a wireless mouse may be a better option. Most will include a 2.4GHz receiver or Bluetooth connectivity, and some from Logitech and Microsoft have unique features that let you connect to multiple devices and even transfer files between them.

Battery - Battery is relevant for wireless mice. A wireless mouse will either use AAA batteries which may less for several weeks or months, or it may be rechargeable. A rechargeable mouse usually doesn't last quite as long as one running off batteries, but it does spare you the hassle of having to buy batteries.

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