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Best Overall: Logitech MX Master 2S at Amazon
"Having the quintessential blend of style and functionality, Logitech's MX Master is undoubtedly the best ergonomic mouse that you can buy."
Best Budget: Anker Ergonomic Wired Mouse at Amazon
"Perfect if you have no use for fancy features and just want a simple yet functional ergonomic mouse that won't break the bank."
Best Design: Microsoft Pro IntelliMouse at Amazon
"The Microsoft Pro Intellimouse is the Cadillac of the wired mouse kingdom— attractive, functional, and reliable."
Best Wired: J-Tech Digital Scroll Endurance at Amazon
"The Scroll Endurance is ideal for users who have to work on computers for long hours with a design that alleviates hand fatigue."
Best Compact: Swiftpoint GT at Amazon
"With a weight of just .84 ounces, the Swiftpoint GT is light as a feather but packs in an expansive feature set that belies its diminutive size."
Best Wireless: Anker AK-UBA at Amazon
"The Anker AK-UBA is the ideal wireless ergonomic mouse, with a thoughtful design that encourages healthy wrist and arm positions."
Best With Trackball: Logitech MX ERGO at Amazon
"The MX ERGO features an industry-leading trackball to create an ergonomic experience that marries extreme precision with personal comfort."
Best Gaming: Razer DeathAdder Elite at Amazon
"Designed to perfectly fit in the palm of your hand, the DeathAdder Elite provides a comfortable experience even with extended hours of usage."
If your hand and wrist starts cramping from hours of working at the computer, it may be time to get an ergonomic mouse. The best ergonomic mice have unique shapes (often vertical) that give your hand a more comfortable grip on the device. They are often also wireless and use AA or rechargeable batteries, allowing you to go days at a time between charges. We tested and researched a number of mice from brands like Logitech, Anker, Microsoft, J-Tech, and Razer to help you pick the best ones.
If your needs are more specific you should also look at our list of best wireless mice and best mice for gaming.
Courtesy of Amazon
Great build quality
Comfortable in the hand
Works with up to three devices
Nowhere to store USB receiver
Not the most compact
Having the quintessential blend of style and functionality, Logitech's MX Master 2S is undoubtedly the best ergonomic mouse that you can buy.
As Logitech's flagship mouse, the MX Master 2S has a unique thumb wheel that makes horizontal navigation extremely simple. Its smart speed-adaptive scroll wheel automatically shifts between scrolling modes in response to your touch. Our reviewer liked the click-to-click mode, which is ideal for precise and ratcheted motion; and the hyper-fast mode, which lets you fly through long documents and Web pages with ease.
The mouse comes with Logitech's high-precision Darkfield sensor that can track movements on just about any surface, even glass (with a minimum thickness of 4mm). Using either the included unifying receiver or Bluetooth, you can connect Logitech MX Master to a total of three (Windows or macOS) computers, and switch between them effortlessly with a button on the mouse's bottom. Its built-in rechargeable battery can go up to 40 days (based on 6 hours of daily use) on a single charge.
The companion Logitech Options software allows you to extend the capabilities of the MX Master even further. You can use it to reassign buttons, add gestures to the thumb wheel, and configure app-specific button functions.
"We tested the mouse out on multiple surfaces and didn’t experience any issues, whether it was a hardwood desk or glass top desk." — Gannon Brugett, Product Tester
Simple and functional
Healthy position with less strain
Additional buttons for better web browsing
If you have no use for fancy features and customization capabilities, and just want a simple yet functional ergonomic mouse that won't break the bank, Anker's wired mouse is going to serve you just fine.
With its scientific ergonomic construction, Anker's wired vertical mouse encourages healthy and neutral "handshake" positions for the wrist and arm, resulting in smoother movement and less overall strain. The mouse has 1000/1600 DPI resolution and utilizes optical tracking technology, which not only provides enhanced sensitivity but also makes for smoother and more precise tracking on a wide variety of surfaces.
Along with a DPI switch button, Anker's wired mouse has two additional buttons (Next and Previous) that make the Web browsing experience even better. A scroll wheel sits in between the vertically mounted left and right buttons. The mouse has a 1.5m (4.9-foot) long cable and uses the standard USB Type-A for connecting with PCs.
The Anker Ergonomic Wired Mouse is backed by an 18-month warranty, as well as lifetime technical support guarantee.
Attractive and functional
Reliable performance for day-to-day work
Minimalist design and rugged braided cable
Doesn't have any extra bells and whistles
Looking for the Cadillac of the wired mouse kingdom? Look no further than the Microsoft Pro Intellimouse, an attractive, functional, and reliable mouse that favors minimalism over extraneous buttons. This decision, among others, makes it an absolutely excellent choice for day-to-day work, precision assignments for those in creative positions, and even gaming.
It has just three mouse buttons: left, right, and a click wheel. All feel wonderfully precise and durable. There's even a subtle LED strip on the mouse chassis to add a bit of glow for nighttime use — if you need a bit of illumination. Its lengthy, sturdy braided cable feels rugged enough to withstand any kind of mouse mishap, and its smooth plastic body has a satisfying grip to it that offers a nice heft. It may seem basic at first glance, but it’s
Works great for long hours
Vertical design to alleviate hand fatigue
Detachable palm rest and tactile buttons
If you don't want to bother with charging (or replacing) batteries and would rather have something that you can just plug in and start using, look no further than J-Tech Digital's Scroll Endurance wired ergonomic mouse.
The Scroll Endurance is ideal for users who have to work on computers for long hours. Its vertical design reduces the torsion of the forearm and wrist caused by regular mice, thus helping in alleviating hand fatigue. The mouse also includes a detachable palm rest that minimizes drag on the desk surface. An easy-to-access DPI button on the top lets you adjust the Scroll Endurance's sensitivity on the fly, and there are multiple sensitivity modes (600/1000/1600 DPI) that you can choose from.
The mouse's vertically mounted left and right buttons are quite tactile, and the scroll wheel between them pulls double duty as the middle button. In addition, it comes with two thumb buttons that can be used to perform Back and Forward functions while browsing the Web.
Weighing around 4.16 ounces and compatible with both USB 2.0 and USB 3.0 ports, J-Tech Digital Scroll Endurance is backed by a one-year free replacement warranty.
Compact size and light weight
Supports wireless USB and Bluetooth
Integrated iOS and Windows apps/programs
Do you think ergonomic mice always have to be bulky in order to be great? Think again. The expansive feature set of Swiftpoint GT utterly belies its diminutive size.
With a weight of just .84 ounces, Swiftpoint GT is light as a feather. Its unique and patented pen-like grip lets you combine natural touch gestures with the precision of a wireless mouse. The mouse is optimized for right-hand use and features dual (wireless USB and Bluetooth) connectivity. This means that it can be used not only with Windows, macOS, and Linux PCs, but also with iOS and Android devices.
In fact, Swiftpoint GT is integrated with iOS and Windows versions of numerous apps/programs, including VMware Horizon Client, Amazon Workspaces, TeamViewer, Jump Desktop, Splashtop Business & Personal, Parallels Client, Sunlogin, Nulanta Remotix, and Mochasoft. The mouse's unique touch gesture technology allows you to scroll and zoom on touchscreen devices sans any effort. With two buttons and a gesture stylus, it has a sensor resolution of 1250 DPI.
Swiftpoint GT's built-in battery can last two to four weeks on a full charge, depending upon the usage. Along with the mouse and USB receiver, you also get a travel case.
Vertical shape for smoother movement
Button to toggle DPI resolutions
Requires AAA batteries
Having a thoughtful design and easy-to-use features, the Anker AK-UBA is the ideal wireless ergonomic mouse for all your computing needs.
Anker AK-UBA mouse has a vertical shape that encourages healthy wrist and arm positions, resulting in smoother movement and lesser overall muscle strain. It comes with 800/1200/1600 DPI resolutions, and a button lets you easily toggle between these. The standard left and right buttons are vertically mounted, and a scroll wheel sits between them. Two additional buttons — Previous and Next — allow you to browse the Web faster and better, and the whole package is backed by an 18-month warranty. The mouse is compatible with Windows, Linux, and macOS.
The AK-UBA wireless mouse from Anker is powered by two AAA batteries. When not in use, the 2.4G USB wireless receiver can be easily stashed away in a slot on the bottom of the mouse.
Unique adjustable hinge
Allows file sharing between two computers
Trackballs are extremely precise since their effective travel range in all directions is virtually limitless. The fact that they don't have to be constantly re-positioned also makes them convenient to use. Many ergonomic mice come with built-in trackballs, and Logitech's MX ERGO is the best among them.
The mouse comes with a unique adjustable hinge that allows you to adjust its angle for personalized comfort, resulting in up to 20 percent lesser muscular strain. The MX ERGO also lets you control two PCs (even those having different operating systems) and switch between them seamlessly, speeding up your workflow.
Its multi-device trackball can be used to share files between two computers using basic Copy and Paste commands. Using the companion Logitech Options software, you can easily configure flow and assign custom functions/tasks to mouse buttons. Speaking of, a dedicated button can be used to change the speed and accuracy of the cursor on the fly, while the precision scroll wheel comes with horizontal scrolling and middle click functionalities. The MX ERGO has a sculpted shape and rubber-top grip, which ensures full palm and finger support for a more comfortable control. Fast and accurate, the mouse's island-style keys are claimed to be able to stand up to 10 million clicks.
Logitech MX ERGO has a built-in rechargeable battery that can go up to four months on a full charge. Also, just one minute of charging can provide up to a full day of use.
Comfortable for hours of use
Great for gamers
Optimized mechanical switches
When it comes to gaming peripherals, Razer is a name that needs no introduction. Its DeathAdder Elite is a slick and feature-laden ergonomic mouse that the gamer in you will surely love.
Designed to perfectly fit in the palm of your hand, the DeathAdder Elite provides a comfortable experience even with extended hours of usage. Featuring Razer's most advanced 5G optical sensor, the mouse has a sensitivity of up to 16,000 DPI, as well as up to 450 IPS with 99.4 percent resolution accuracy. It also has specially optimized mechanical switches that are claimed to be durable enough for up to 50 million clicks.
In fact, it's these features that make the mouse popular for eSports gaming tournaments. Using the companion Razer Synapse software, you can customize the functions synced to the mouse's programmable buttons. Furthermore, Razer's Chroma RGB full-spectrum lighting feature lets you personalize the mouse with up to 16.8 million lighting options. Its rubberized side grips make for a comfortable hold at all times, even during quick swipe gestures.
Razer DeathAdder Elite comes with a gaming-grade scroll wheel that features precise tactile feedback. A braided USB cord perfectly complements the mouse's sharp design.
"The Razer DeathAdder Elite is a great wired mouse in terms of both comfort and gaming. The mix of high precision and customization buttons and lighting makes it great for work and play." — Alice Newcome-Beill, Associate Commerce Editor
If you're feeling arm and wrist strain, an ergonomic keyboard like the Logitech MX Master 2S may be what you need. The mouse is wireless, has a comfortable design that reduces strain without leasing precision on clicks. There's also some special features like speed-adaptive scroll to shift scrolling modes, and a unifying receiver and Bluetooth to connect to three devices at the same time and work between them. For a more affordable option, we like the Anker Ergonomic Wired Mouse. It's not wireless, but it's a vertical mouse which encourages a healthy grip position, and it has solid tracking and functionality.
Gannon Brugett has more than a decade of experience as a tech and photojournalist and photographer. He's familiar with computer equipment and peripherals, particularly when it comes to video and photo editing. He enjoyed the MX Master 2S for its high-quality build and comfort for long hours of work, not to mention its useful functionality.
Alice Newcome-Beill is Associate Commerce Editor at Lifewire. She's previously been published on PCMag, PC Gamer, and GamesRadar. She even built her own gaming rig, so there are few people who know computer peripherals better than her. Alice likes the Razer DeathAdder Elite for its precision, especially when it comes to MOBAs and fast-paced shooters.
David Dean has worked in IT for 15 years in a variety of roles. He's also the founder of his own travel technology website and travel blog making him very familiar with wireless mice, vertical mice, and just about any variation of computer mice.
Comfort/Design - The obvious feature of a ergonomic mouse is comfort. One common type of design you'll see is vertical mice, where a mouse is shaped in a way so you grip it in a "handshake" position. This puts less strain on your arms and wrist, though there is a learning curve to get used to the new button layouts and movements. Another design you might encounter is one often used by Logitech, with a wider mouse with a larger thumb grip to rest your hand comfortably. It might come with additional buttons like a scroll wheel or trackball to make navigation easier.
Wired/Wireless - A wired ergonomic mouse has the advantage of not needing to be recharged. It can also work out of the box with less setup. However, the inclusion of a cable is annoying to some and clutters desks. If you like to a clean work space or are often working across multiple devices, a wireless mouse may be a better option. Most will include a 2.4GHz receiver or Bluetooth connectivity, and some from Logitech and Microsoft have unique features that let you connect to multiple devices and even transfer files between them.
Battery - Battery is relevant for wireless mice. A wireless mouse will either use AAA batteries which may less for several weeks or months, or it may be rechargeable. A rechargeable mouse usually doesn't last quite as long as one running off batteries, but it does spare you the hassle of having to buy batteries.